InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SLC25A4

Summary

InnateDB Gene

IDBG-628540.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SLC25A4

Gene Name

ADP/ATP translocase 1

Synonyms

ANT1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000013208

Encoded Proteins

IDBP-679906

ADP/ATP translocase 1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000151729:
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Sep 2009]
This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Mutations in this gene have been shown to result in autosomal dominant progressive external opthalmoplegia and familial hypertrophic cardiomyopathy. [provided by RefSeq, Jun 2013]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 27:14546020-14550037

Strand

Forward strand

Band

Transcripts

ENSBTAT00000017580

ENSBTAP00000017580

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 17 interaction(s) predicted by orthology.