InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.29026

Summary

InnateDB Gene

IDBG-628704.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.29026

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000012870

Encoded Proteins

IDBP-680088

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112175:
This gene encodes a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. These proteins are synthesized as prepropeptides, cleaved, and then processed into dimeric proteins. This protein may act as an important signaling molecule within the trabecular meshwork and optic nerve head, and may play a potential role in glaucoma pathogenesis. This gene is differentially regulated during the formation of various tumors. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 23:4390362-4533900

Strand

Forward strand

Band

Transcripts

ENSBTAT00000017102

ENSBTAP00000017102

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008083	growth factor activity
GO:0070700	BMP receptor binding

Biological Process

GO:0001501	skeletal system development
GO:0003323	type B pancreatic cell development
GO:0007389	pattern specification process
GO:0008285	negative regulation of cell proliferation
GO:0010862	positive regulation of pathway-restricted SMAD protein phosphorylation
GO:0010894	negative regulation of steroid biosynthetic process
GO:0030539	male genitalia development
GO:0032348	negative regulation of aldosterone biosynthetic process
GO:0040007	growth
GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0050679	positive regulation of epithelial cell proliferation
GO:1900006	positive regulation of dendrite development
GO:2000065	negative regulation of cortisol biosynthetic process
GO:2000105	positive regulation of DNA-dependent DNA replication