Bos taurus Gene: TINAG
Summary
InnateDB Gene IDBG-628721.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TINAG
Gene Name Tubulointerstitial nephritis antigen
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012652
Encoded Proteins
Tubulointerstitial nephritis antigen
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137251:
This gene encodes a glycoprotein that is restricted within the kidney to the basement membranes underlying the epithelium of Bowman's capsule and proximal and distal tubules. Autoantibodies against this protein are found in sera of patients with tubulointerstital nephritis, membranous nephropathy and anti-glomerular basement membrane nephritis. Ontogeny studies suggest that the expression of this antigen is developmentally regulated in a precise spatial and temporal pattern throughout nephrogenesis. [provided by RefSeq, Nov 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:5953509-6059979
Strand Reverse strand
Band
Transcripts
ENSBTAT00000016790 ENSBTAP00000016790
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0008234 cysteine-type peptidase activity
GO:0030247 polysaccharide binding
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0007155 cell adhesion
Cellular Component
GO:0005576 extracellular region
GO:0005578 proteinaceous extracellular matrix
GO:0005604 basement membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt Q3SZI1
TrEMBL
UniProt Splice Variant
Entrez Gene 512517
UniGene Bt.29080
RefSeq NM_001035107 XM_005223239
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC102843
GenPept AAI02844
RNA Seq Atlas 512517