Version 5.4
Bos taurus Gene: IL34
Summary
InnateDB Gene IDBG-628785.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL34
Gene Name Interleukin-34
Synonyms C18H16ORF77; IL-34
Species Bos taurus
Ensembl Gene ENSBTAG00000009357
Encoded Proteins
IDBP-680163
Interleukin-34
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000157368:
Interleukin-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R; MIM 164770) (Lin et al., 2008 [PubMed 18467591]).[supplied by OMIM, May 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:1548806-1608706
Strand Reverse strand
Band
Transcripts
ENSBTAT00000049652 ENSBTAP00000046513
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
GO:0005157 macrophage colony-stimulating factor receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0001934 positive regulation of protein phosphorylation
GO:0002376 immune system process
GO:0006954 inflammatory response
GO:0008284 positive regulation of cell proliferation
GO:0045087 innate immune response
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000157368
View Gene Order
ENSMUSG00000031750
View Gene Order
Cross-References
SwissProt A6QL48
TrEMBL
UniProt Splice Variant
Entrez Gene 508292
UniGene Bt.53591
RefSeq NM_001100324 XM_005218326 XM_005218327 XM_005218328 XM_005218329 XM_005218330 XM_005218331 XM_005218332
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC146187
GenPept AAI46188
RNA Seq Atlas 508292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca