Bos taurus Gene: SLC39A7
Summary
InnateDB Gene IDBG-628949.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC39A7
Gene Name zinc transporter SLC39A7 precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008191
Encoded Proteins
solute carrier family 39, member 7
solute carrier family 39, member 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112473:
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Nov 2011]
The protein encoded by this gene transports zinc from the Golgi and endoplasmic reticulum to the cytoplasm. This transport may be important for activation of tyrosine kinases, some of which could be involved in cancer progression. Therefore, modulation of the encoded protein could be useful as a therapeutic agent against cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:7327198-7331690
Strand Forward strand
Band
Transcripts
ENSBTAT00000052666 ENSBTAP00000050674
ENSBTAT00000010771 ENSBTAP00000010771
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0046873 metal ion transmembrane transporter activity
Biological Process
GO:0030001 metal ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Zinc influx into cells by the SLC39 gene family pathway
Metal ion SLC transporters pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
Transmembrane transport of small molecules pathway
Zinc transporters pathway
SLC-mediated transmembrane transport pathway
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
SLC-mediated transmembrane transport pathway
Zinc influx into cells by the SLC39 gene family pathway
Zinc transporters pathway
Transmembrane transport of small molecules pathway
Metal ion SLC transporters pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q0P5C9
UniProt Splice Variant
Entrez Gene 540716
UniGene Bt.8102
RefSeq XM_005223259 NM_001076237
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120222 BT030517 DAAA02054891 DAAA02054892
GenPept AAI20223 ABQ12957
RNA Seq Atlas 540716