Bos taurus Gene: PDGFD
Summary
InnateDB Gene IDBG-628975.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDGFD
Gene Name platelet-derived growth factor D
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000034827
Encoded Proteins
platelet-derived growth factor D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000170962:
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:4501435-4788300
Strand Forward strand
Band
Transcripts
ENSBTAT00000049292 ENSBTAP00000046207
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005161 platelet-derived growth factor receptor binding
GO:0008083 growth factor activity
Biological Process
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0050730 regulation of peptidyl-tyrosine phosphorylation
GO:0051781 positive regulation of cell division
GO:0071230 cellular response to amino acid stimulus
Cellular Component
GO:0016020 membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Signaling by PDGF pathway
Signal Transduction pathway
Signaling by PDGF pathway
Signal Transduction pathway
KEGG
Regulation of actin cytoskeleton pathway
Gap junction pathway
Melanoma pathway
Prostate cancer pathway
Focal adhesion pathway
Cytokine-cytokine receptor interaction pathway
Gap junction pathway
Melanoma pathway
Regulation of actin cytoskeleton pathway
Prostate cancer pathway
Focal adhesion pathway
INOH
PID NCI
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
PDGF receptor signaling network
Cross-References
SwissProt
TrEMBL A4IFC0
UniProt Splice Variant
Entrez Gene 525931
UniGene Bt.40070
RefSeq NM_001083706
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134505 DAAA02039829 DAAA02039830 DAAA02039831 DAAA02039832 DAAA02039833 DAAA02039834 DAAA02039835 DAAA02039836 DAAA02039837 DAAA02039838 DAAA02039839 DAAA02039840 DAAA02039841 DAAA02039842 DAAA02039843
GenPept AAI34506
RNA Seq Atlas 525931