Version 5.4
| Homo sapiens Gene: PDGFD | |||||||||||||||||||
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| Summary | |||||||||||||||||||
| InnateDB Gene | IDBG-69503.6 | ||||||||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
| Gene Symbol | PDGFD | ||||||||||||||||||
| Gene Name | platelet derived growth factor D | ||||||||||||||||||
| Synonyms | |||||||||||||||||||
| Species | Homo sapiens | ||||||||||||||||||
| Ensembl Gene | ENSG00000170962 | ||||||||||||||||||
| Encoded Proteins |
platelet derived growth factor D
platelet derived growth factor D
platelet derived growth factor D
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
| Entrez Gene | |||||||||||||||||||
| Summary |
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene. [provided by RefSeq, Jul 2008] |
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| Gene Information | |||||||||||||||||||
| Type | Protein coding | ||||||||||||||||||
| Genomic Location | Chromosome 11:103907186-104164379 | ||||||||||||||||||
| Strand | Reverse strand | ||||||||||||||||||
| Band | q22.3 | ||||||||||||||||||
| Transcripts |
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| Interactions | |||||||||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||||||||
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Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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| Pathways | |||||||||||||||||||
| NETPATH | |||||||||||||||||||
| REACTOME |
Signaling by PDGF pathway
Signal Transduction pathway
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| KEGG |
Regulation of actin cytoskeleton pathway
Gap junction pathway
Melanoma pathway
Prostate cancer pathway
Focal adhesion pathway
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| INOH | |||||||||||||||||||
| PID NCI |
Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
PDGF receptor signaling network
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| Cross-References | |||||||||||||||||||
| SwissProt | Q9GZP0 | ||||||||||||||||||
| TrEMBL | |||||||||||||||||||
| UniProt Splice Variant | |||||||||||||||||||
| Entrez Gene | 80310 | ||||||||||||||||||
| UniGene | Hs.352298 Hs.598726 Hs.627559 | ||||||||||||||||||
| RefSeq | NM_033135 NM_025208 | ||||||||||||||||||
| HUGO | HGNC:30620 | ||||||||||||||||||
| OMIM | 609673 | ||||||||||||||||||
| CCDS | CCDS8326 CCDS41703 | ||||||||||||||||||
| HPRD | 17830 | ||||||||||||||||||
| IMGT | |||||||||||||||||||
| EMBL | AB033832 AF113216 AF335584 AF336376 AK292801 AY027517 AY027518 AY359116 BC030645 CH471065 | ||||||||||||||||||
| GenPept | AAG39287 AAH30645 AAK20081 AAK20082 AAK38840 AAK56136 AAQ89474 BAB18903 BAF85490 EAW67045 | ||||||||||||||||||
| RNA Seq Atlas | 80310 | ||||||||||||||||||