InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.96766

Summary

InnateDB Gene

IDBG-629054.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.96766

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000046409

Encoded Proteins

IDBP-680445

Early growth response 2 protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122877:
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 28:19012870-19015927

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000064240

ENSBTAP00000055288

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.

Predicted by orthology
Total	23 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001102	RNA polymerase II activating transcription factor binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003682	chromatin binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0044212	transcription regulatory region DNA binding
GO:0046872	metal ion binding

Biological Process

GO:0006355	regulation of transcription, DNA-templated
GO:0006366	transcription from RNA polymerase II promoter
GO:0006611	protein export from nucleus
GO:0007622	rhythmic behavior
GO:0008045	motor neuron axon guidance
GO:0014037	Schwann cell differentiation
GO:0021569	rhombomere 3 development
GO:0021612	facial nerve structural organization
GO:0021660	rhombomere 3 formation
GO:0021666	rhombomere 5 formation
GO:0030278	regulation of ossification
GO:0035284	brain segmentation
GO:0035914	skeletal muscle cell differentiation
GO:0042552	myelination
GO:0043066	negative regulation of apoptotic process
GO:0045444	fat cell differentiation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:0048168	regulation of neuronal synaptic plasticity
GO:0071310	cellular response to organic substance
GO:0071320	cellular response to cAMP
GO:0071371	cellular response to gonadotropin stimulus