Version 5.4
Bos taurus Gene: EIF2D
Summary
InnateDB Gene IDBG-629071.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol EIF2D
Gene Name Eukaryotic translation initiation factor 2D
Synonyms LGTN
Species Bos taurus
Ensembl Gene ENSBTAG00000010432
Encoded Proteins
IDBP-680480
Eukaryotic translation initiation factor 2D
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143486:
This gene encodes a translation initiation factor involved in the recruitment and delivery of aminoacyl-tRNAs to the P-site of the eukaryotic ribosome in a GTP-independent manner. This gene was previously referred to as ligatin, but is now known to localize to the cytoplasm and localize and function with translation factors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 16:4221210-4242621
Strand Reverse strand
Band
Transcripts
ENSBTAT00000013769 ENSBTAP00000013769
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
GO:0005515 protein binding
Biological Process
GO:0001731 formation of translation preinitiation complex
GO:0002192 IRES-dependent translational initiation
GO:0006412 translation
GO:0006413 translational initiation
GO:0032790 ribosome disassembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0022627 cytosolic small ribosomal subunit
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143486
View Gene Order
ENSMUSG00000026427
View Gene Order
Cross-References
SwissProt Q58CR3
TrEMBL G8JKW9
UniProt Splice Variant
Entrez Gene 511844
UniGene Bt.59019
RefSeq NM_001035104
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC114158 BT021884 DAAA02041966
GenPept AAI14159 AAX46731
RNA Seq Atlas 511844

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca