Version 5.4
| Bos taurus Gene: HERC4 | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-629122.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | HERC4 | ||||||
| Gene Name | probable E3 ubiquitin-protein ligase HERC4 | ||||||
| Synonyms | |||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000014029 | ||||||
| Encoded Proteins |
hect domain and RLD 4
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000148634:
HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710)-like domain (RLD). The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins (Hochrainer et al., 2005 [PubMed 15676274]).[supplied by OMIM, Mar 2008] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 28:24587774-24715401 | ||||||
| Strand | Reverse strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME | |||||||
| KEGG |
Ubiquitin mediated proteolysis pathway
Ubiquitin mediated proteolysis pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | E1BAV2 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 533336 | ||||||
| UniGene | Bt.15687 | ||||||
| RefSeq | NM_001076894 XM_005226412 XM_005226414 XM_005226415 | ||||||
| HUGO | HGNC:24521 | ||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | DAAA02061808 DAAA02061809 DAAA02061810 | ||||||
| GenPept | |||||||
| RNA Seq Atlas | 533336 | ||||||