InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SNRNP200

Summary

InnateDB Gene

IDBG-629205.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNRNP200

Gene Name

U5 small nuclear ribonucleoprotein 200 kDa helicase

Synonyms

ASCC3L1

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000848

Encoded Proteins

IDBP-680742

small nuclear ribonucleoprotein 200kDa (U5)

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144028:
Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 11:2343017-2368147

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000001130

ENSBTAP00000001130

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 93 interaction(s) predicted by orthology.

Predicted by orthology
Total	93 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0004004	ATP-dependent RNA helicase activity
GO:0004386	helicase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008026	ATP-dependent helicase activity
GO:0016787	hydrolase activity
GO:0017111	nucleoside-triphosphatase activity
GO:0042802	identical protein binding
GO:0044822	poly(A) RNA binding