Bos taurus Gene: PLIN
Summary
InnateDB Gene IDBG-629209.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PLIN
Gene Name perilipin-1
Synonyms PLIN
Species Bos taurus
Ensembl Gene ENSBTAG00000015350
Encoded Proteins
perilipin-1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166819:
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5\' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:21502826-21516686
Strand Reverse strand
Band
Transcripts
ENSBTAT00000020406 ENSBTAP00000020406
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0016042 lipid catabolic process
Cellular Component
GO:0005811 lipid particle
GO:0005829 cytosol
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
Transcriptional regulation of white adipocyte differentiation pathway
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Developmental Biology pathway
KEGG
PPAR signaling pathway pathway
PPAR signaling pathway pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A4IFB3
UniProt Splice Variant
Entrez Gene 520598
UniGene Bt.68730 Bt.82464
RefSeq NM_001083699 XM_005221820 XM_005221821 XM_005221822 XM_005221823
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134495 DAAA02052146
GenPept AAI34496
RNA Seq Atlas 515608 520598