Bos taurus Gene: PLIN | |||||||
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Summary | |||||||
InnateDB Gene | IDBG-629209.3 | ||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
Gene Symbol | PLIN | ||||||
Gene Name | perilipin-1 | ||||||
Synonyms | PLIN | ||||||
Species | Bos taurus | ||||||
Ensembl Gene | ENSBTAG00000015350 | ||||||
Encoded Proteins |
perilipin-1
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Protein Structure | |||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||
Entrez Gene | |||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166819:
The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] The protein encoded by this gene coats lipid storage droplets in adipocytes, thereby protecting them until they can be broken down by hormone-sensitive lipase. The encoded protein is the major cAMP-dependent protein kinase substrate in adipocytes and, when unphosphorylated, may play a role in the inhibition of lipolysis. Alternatively spliced transcript variants varying in the 5\' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Feb 2009] |
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Gene Information | |||||||
Type | Protein coding | ||||||
Genomic Location | Chromosome 21:21502826-21516686 | ||||||
Strand | Reverse strand | ||||||
Band | |||||||
Transcripts |
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Interactions | |||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
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Gene Ontology | |||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Pathway Predictions based on Human Orthology Data | |||||||
NETPATH | |||||||
REACTOME |
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Transcriptional regulation of white adipocyte differentiation pathway
Developmental Biology pathway
Metabolism of lipids and lipoproteins pathway
Metabolism pathway
Lipid digestion, mobilization, and transport pathway
Transcriptional regulation of white adipocyte differentiation pathway
Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis pathway
Metabolism pathway
Metabolism of lipids and lipoproteins pathway
Lipid digestion, mobilization, and transport pathway
Developmental Biology pathway
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KEGG |
PPAR signaling pathway pathway
PPAR signaling pathway pathway
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INOH | |||||||
PID NCI | |||||||
Cross-References | |||||||
SwissProt | |||||||
TrEMBL | A4IFB3 | ||||||
UniProt Splice Variant | |||||||
Entrez Gene | 520598 | ||||||
UniGene | Bt.68730 Bt.82464 | ||||||
RefSeq | NM_001083699 XM_005221820 XM_005221821 XM_005221822 XM_005221823 | ||||||
HUGO | |||||||
OMIM | |||||||
CCDS | |||||||
HPRD | |||||||
IMGT | |||||||
EMBL | BC134495 DAAA02052146 | ||||||
GenPept | AAI34496 | ||||||
RNA Seq Atlas | 515608 520598 | ||||||