Version 5.4
Bos taurus Gene: SGCE
Summary
InnateDB Gene IDBG-629225.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SGCE
Gene Name epsilon-sarcoglycan
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021282
Encoded Proteins
IDBP-680629
epsilon-sarcoglycan
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127990:
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:11840470-11911742
Strand Reverse strand
Band
Transcripts
ENSBTAT00000028355 ENSBTAP00000028355
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016012 sarcoglycan complex
GO:0016020 membrane
GO:0032590 dendrite membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000127990
View Gene Order
ENSMUSG00000004631
View Gene Order
Cross-References
SwissProt
TrEMBL F1MYZ0 Q6U8D2
UniProt Splice Variant
Entrez Gene 407209
UniGene Bt.30480
RefSeq NM_001075145
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AY376070 DAAA02009788
GenPept AAR04855
RNA Seq Atlas 407209

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca