Version 5.4
Mus musculus Gene: Sgce
Summary
InnateDB Gene IDBG-127960.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Sgce
Gene Name sarcoglycan, epsilon
Synonyms e-SG
Species Mus musculus
Ensembl Gene ENSMUSG00000004631
Encoded Proteins
IDBP-127962
sarcoglycan, epsilon
IDBP-127964
sarcoglycan, epsilon
IDBP-127966
sarcoglycan, epsilon
IDBP-249313
sarcoglycan, epsilon
IDBP-249315
sarcoglycan, epsilon
IDBP-532807
sarcoglycan, epsilon
IDBP-537682
sarcoglycan, epsilon
IDBP-539051
sarcoglycan, epsilon
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000127990:
This gene encodes the epsilon member of the sarcoglycan family. Sarcoglycans are transmembrane proteins that are components of the dystrophin-glycoprotein complex, which link the actin cytoskeleton to the extracellular matrix. Unlike other family members which are predominantly expressed in striated muscle, the epsilon sarcoglycan is more broadly expressed. Mutations in this gene are associated with myoclonus-dystonia syndrome. This gene is imprinted, with preferential expression from the paternal allele. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:4674350-4747204
Strand Reverse strand
Band A1
Transcripts
ENSMUST00000004750 ENSMUSP00000004750
ENSMUST00000090686 ENSMUSP00000088185
ENSMUST00000101677 ENSMUSP00000099200
ENSMUST00000115579 ENSMUSP00000111242
ENSMUST00000115577 ENSMUSP00000111240
ENSMUST00000153284
ENSMUST00000126151 ENSMUSP00000120718
ENSMUST00000133306 ENSMUSP00000121964
ENSMUST00000123907 ENSMUSP00000120910
ENSMUST00000130428
ENSMUST00000128109
ENSMUST00000139029
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016010 dystrophin-associated glycoprotein complex
GO:0016012 sarcoglycan complex
GO:0016020 membrane
GO:0030425 dendrite
GO:0032590 dendrite membrane
GO:0042383 sarcolemma
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000127990
View Gene Order
ENSBTAG00000021282
Not yet available
Cross-References
SwissProt O70258
TrEMBL
UniProt Splice Variant
Entrez Gene 20392
UniGene Mm.400607 Mm.484629 Mm.8739
RefSeq NM_001130188 XM_006505021 NM_001130189 NM_001130190 NM_001130191 NM_011360 XM_006505020
OMIM
CCDS CCDS51718 CCDS51715 CCDS51716 CCDS51717
HPRD
IMGT
MGI ID MGI:1329042
MGI Symbol Sgce
EMBL AF031919 AF103877 AK076102 BC012665
GenPept AAC14020 AAF21895 AAH12665 BAC36184
RNA Seq Atlas 20392

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca