Version 5.4
Bos taurus Gene: RNASEH2B
Summary
InnateDB Gene IDBG-629240.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RNASEH2B
Gene Name Ribonuclease H2 subunit B
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020149
Encoded Proteins
IDBP-680647
Ribonuclease H2 subunit B
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000136104:
RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). [provided by RefSeq, Nov 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:20417680-20480648
Strand Forward strand
Band
Transcripts
ENSBTAT00000026838 ENSBTAP00000026838
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006401 RNA catabolic process
Cellular Component
GO:0005634 nucleus
GO:0032299 ribonuclease H2 complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000136104
View Gene Order
ENSMUSG00000021932
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa03030
DNA replication pathway
mmu03030
DNA replication pathway
INOH
PID NCI
Cross-References
SwissProt Q3ZBI3
TrEMBL
UniProt Splice Variant
Entrez Gene 509258
UniGene Bt.91620
RefSeq NM_001166566
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC103280
GenPept AAI03281
RNA Seq Atlas 509258

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca