Version 5.4
Bos taurus Gene: LPO
Summary
InnateDB Gene IDBG-629359.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LPO
Gene Name Lactoperoxidase
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000012780
Encoded Proteins
IDBP-680785
Lactoperoxidase
IDBP-680786
Lactoperoxidase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000167419:
This gene encodes an oxidoreductase secreted from salivary, mammary, and other mucosal glands that functions as a natural antibacterial agent. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 19:9441748-9471498
Strand Forward strand
Band
Transcripts
ENSBTAT00000016986 ENSBTAP00000016986
ENSBTAT00000066160 ENSBTAP00000054415
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004601 peroxidase activity
GO:0005509 calcium ion binding
GO:0016491 oxidoreductase activity
GO:0020037 heme binding
GO:0036393 thiocyanate peroxidase activity
GO:0046872 metal ion binding
Biological Process
GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste
GO:0006979 response to oxidative stress
GO:0018969 thiocyanate metabolic process
GO:0019731 antibacterial humoral response
GO:0042742 defense response to bacterium
GO:0042744 hydrogen peroxide catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0016323 basolateral plasma membrane
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000167419
View Gene Order
ENSMUSG00000009356
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04970
Salivary secretion pathway
mmu04970
Salivary secretion pathway
INOH
PID NCI
Cross-References
SwissProt P80025
TrEMBL G3MXZ0
UniProt Splice Variant
Entrez Gene 280844
UniGene Bt.4784
RefSeq NM_173933 XM_005219872 XM_005219873
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02048316 M58150
GenPept AAA62714
RNA Seq Atlas 280844

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca