InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.83070

Summary

InnateDB Gene

IDBG-629417.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.83070

Gene Name

Uncharacterized protein

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000016525

Encoded Proteins

IDBP-680901

Uncharacterized protein

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000213949:
This gene encodes the alpha 1 subunit of integrin receptors. This protein heterodimerizes with the beta 1 subunit to form a cell-surface receptor for collagen and laminin. The heterodimeric receptor is involved in cell-cell adhesion and may play a role in inflammation and fibrosis. The alpha 1 subunit contains an inserted (I) von Willebrand factor type I domain which is thought to be involved in collagen binding. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 20:26116747-26227530

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000034583

ENSBTAP00000034473

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 10 interaction(s) predicted by orthology.

Predicted by orthology
Total	10 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0019903	protein phosphatase binding

Biological Process

GO:0007155	cell adhesion
GO:0007229	integrin-mediated signaling pathway
GO:0008285	negative regulation of cell proliferation
GO:0030593	neutrophil chemotaxis
GO:0032516	positive regulation of phosphoprotein phosphatase activity
GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway
GO:0045123	cellular extravasation

Cellular Component

GO:0005925	focal adhesion
GO:0008305	integrin complex
GO:0009897	external side of plasma membrane
GO:0009986	cell surface
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0045178	basal part of cell
GO:0070062	extracellular vesicular exosome