InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: GPR161

Summary

InnateDB Gene

IDBG-629444.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GPR161

Gene Name

G protein-coupled receptor 161

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000000616

Encoded Proteins

IDBP-680859

G protein-coupled receptor 161

IDBP-680862

G protein-coupled receptor 161

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143147:
Upon ligand binding, G protein-coupled receptors, such as GPR161, activate cytoplasmic G proteins (see GNAS, MIM 139320), allowing the receptors to transduce extracellular signals across the plasma membrane into the cell. Phosphorylation of the receptor attenuates signaling (Matteson et al., 2008 [PubMed 18250320]).[supplied by OMIM, Aug 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 3:553190-575832

Strand

Forward strand

Band

Transcripts

ENSBTAT00000000809	ENSBTAP00000000809
ENSBTAT00000066044	ENSBTAP00000054197

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004871	signal transducer activity
GO:0004930	G-protein coupled receptor activity

Biological Process

GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007275	multicellular organismal development
GO:0030819	positive regulation of cAMP biosynthetic process
GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning

Cellular Component

GO:0005886	plasma membrane
GO:0005929	cilium
GO:0016020	membrane
GO:0016021	integral component of membrane
GO:0042995	cell projection
GO:0055037	recycling endosome
GO:0060170	ciliary membrane
GO:0072372	primary cilium