Version 5.4
Bos taurus Gene: POU2F1
Summary
InnateDB Gene IDBG-629561.2
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol POU2F1
Gene Name POU domain, class 2, transcription factor 1
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000024534
Encoded Proteins
IDBP-680993
POU domain, class 2, transcription factor 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000143190:
The OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al., 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160-amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.[supplied by OMIM, Jul 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:1328186-1415265
Strand Reverse strand
Band
Transcripts
ENSBTAT00000034119 ENSBTAP00000034020
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 56 interaction(s) predicted by orthology.
Predicted by orthology
Total 56 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000143190
View Gene Order
ENSMUSG00000026565
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
REACT_22339
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_571
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
REACT_281
RNA Polymerase III Transcription Initiation pathway
REACT_1371
RNA Polymerase III Transcription pathway
REACT_21352
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_71
Gene Expression pathway
REACT_244415
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription pathway
REACT_233104
RNA Polymerase III Transcription Initiation pathway
REACT_261233
RNA Polymerase III Abortive And Retractive Initiation pathway
REACT_233572
Gene Expression pathway
REACT_237241
RNA Polymerase III Transcription pathway
REACT_240508
RNA Polymerase III Transcription Initiation From Type 3 Promoter pathway
KEGG
INOH
PID NCI
tcrcalciumpathway
Calcium signaling in the CD4+ TCR pathway
nfat_tfpathway
Calcineurin-regulated NFAT-dependent transcription in lymphocytes
atf2_pathway
ATF-2 transcription factor network
reg_gr_pathway
Glucocorticoid receptor regulatory network
ar_tf_pathway
Regulation of Androgen receptor activity
hnf3apathway
FOXA1 transcription factor network
Cross-References
SwissProt
TrEMBL F1MMF9 Q0VC94
UniProt Splice Variant
Entrez Gene 512840
UniGene Bt.39352
RefSeq NM_001075582 XM_005203424 XM_005203425 XM_005203426 XM_005203427 XM_005203428
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC120288 DAAA02006756 DAAA02006757 DAAA02006758
GenPept AAI20289
RNA Seq Atlas 512840

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca