Version 5.4
| Bos taurus Gene: GUCY1A2 | |||||||||||||
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| Summary | |||||||||||||
| InnateDB Gene | IDBG-629698.3 | ||||||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
| Gene Symbol | GUCY1A2 | ||||||||||||
| Gene Name | guanylate cyclase soluble subunit alpha-2 | ||||||||||||
| Synonyms | |||||||||||||
| Species | Bos taurus | ||||||||||||
| Ensembl Gene | ENSBTAG00000044144 | ||||||||||||
| Encoded Proteins |
guanylate cyclase 1, soluble, alpha 2
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| Protein Structure | |||||||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
| Entrez Gene | |||||||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000152402:
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3\',5\'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] |
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| Gene Information | |||||||||||||
| Type | Protein coding | ||||||||||||
| Genomic Location | Chromosome 15:16604381-17100655 | ||||||||||||
| Strand | Forward strand | ||||||||||||
| Band | |||||||||||||
| Transcripts |
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| Interactions | |||||||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 9 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||||||
| NETPATH | |||||||||||||
| REACTOME |
Nitric oxide stimulates guanylate cyclase pathway
Platelet homeostasis pathway
Hemostasis pathway
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| KEGG |
Gap junction pathway
Purine metabolism pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
Salivary secretion pathway
Gap junction pathway
Purine metabolism pathway
Long-term depression pathway
Vascular smooth muscle contraction pathway
Salivary secretion pathway
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| INOH |
Purine nucleotides nucleosides metabolism pathway
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| PID NCI | |||||||||||||
| Cross-References | |||||||||||||
| SwissProt | |||||||||||||
| TrEMBL | E1BP75 | ||||||||||||
| UniProt Splice Variant | |||||||||||||
| Entrez Gene | 613600 | ||||||||||||
| UniGene | Bt.106452 Bt.88963 | ||||||||||||
| RefSeq | NM_001191341 | ||||||||||||
| HUGO | |||||||||||||
| OMIM | |||||||||||||
| CCDS | |||||||||||||
| HPRD | |||||||||||||
| IMGT | |||||||||||||
| EMBL | DAAA02040158 DAAA02040159 DAAA02040160 DAAA02040161 DAAA02040162 DAAA02040163 DAAA02040164 DAAA02040165 DAAA02040166 DAAA02040167 DAAA02040168 DAAA02040169 DAAA02040170 DAAA02040171 DAAA02040172 | ||||||||||||
| GenPept | |||||||||||||
| RNA Seq Atlas | 613600 | ||||||||||||
| Transcript Frequencies | |||||||||||||
| Tag Count based mRNA-Abundances across 87 different Tissues (TPM).
Based on Data from Bovine Gene Atlas |
(Move your mouse over the image to view a more detailed version) |
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