Version 5.4
Homo sapiens Gene: ADAP1
Summary
InnateDB Gene IDBG-6297.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADAP1
Gene Name ArfGAP with dual PH domains 1
Synonyms CENTA1; GCS1L; p42IP4
Species Homo sapiens
Ensembl Gene ENSG00000105963
Encoded Proteins
IDBP-6299
ArfGAP with dual PH domains 1
IDBP-361050
ArfGAP with dual PH domains 1
IDBP-361051
ArfGAP with dual PH domains 1
IDBP-361055
ArfGAP with dual PH domains 1
IDBP-361056
ArfGAP with dual PH domains 1
IDBP-361059
ArfGAP with dual PH domains 1
IDBP-361061
ArfGAP with dual PH domains 1
IDBP-361063
ArfGAP with dual PH domains 1
IDBP-589245
ArfGAP with dual PH domains 1
IDBP-807609
ArfGAP with dual PH domains 1
IDBP-807610
ArfGAP with dual PH domains 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 7:897901-955407
Strand Reverse strand
Band p22.3
Transcripts
ENST00000265846 ENSP00000265846
ENST00000449296 ENSP00000407267
ENST00000446141 ENSP00000414436
ENST00000453175 ENSP00000409129
ENST00000437486 ENSP00000404217
ENST00000454383 ENSP00000391315
ENST00000453823 ENSP00000416545
ENST00000435943 ENSP00000394973
ENST00000478000
ENST00000495809
ENST00000481406
ENST00000463358
ENST00000477906
ENST00000488527
ENST00000495686
ENST00000539900 ENSP00000442682
ENST00000611167 ENSP00000481154
ENST00000617043 ENSP00000478011
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
Experimentally validated
Total 31 [view]
Protein-Protein 31 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding
GO:0008060 ARF GTPase activator activity
GO:0008270 zinc ion binding
GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0032312 regulation of ARF GTPase activity
GO:0043087 regulation of GTPase activity
GO:0043547 positive regulation of GTPase activity
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005886 plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000056413
View Gene Order
ENSBTAG00000015952
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
pi3kcipathway
Class I PI3K signaling events
arf6_pathway
Arf6 signaling events
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.602573 Hs.729623
RefSeq NM_001284308 NM_001284309 NM_001284310 NM_001284311 NM_006869
HUGO
OMIM
CCDS CCDS5318 CCDS64576 CCDS64577 CCDS75558
HPRD 09733
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca