Version 5.4
Bos taurus Gene: MEOX2
Summary
InnateDB Gene IDBG-629801.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MEOX2
Gene Name homeobox protein MOX-2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000003238
Encoded Proteins
IDBP-681215
homeobox protein MOX-2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000106511:
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008]
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer\'s disease. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:23943520-24019359
Strand Reverse strand
Band
Transcripts
ENSBTAT00000004198 ENSBTAP00000004198
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.
Predicted by orthology
Total 19 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000980 RNA polymerase II distal enhancer sequence-specific DNA binding
GO:0001077 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001205 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0005515 protein binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0001525 angiogenesis
GO:0001757 somite specification
GO:0006355 regulation of transcription, DNA-templated
GO:0007519 skeletal muscle tissue development
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0060021 palate development
GO:0060173 limb development
GO:0070997 neuron death
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000106511
View Gene Order
ENSMUSG00000036144
View Gene Order
Cross-References
SwissProt
TrEMBL A5D7C5
UniProt Splice Variant
Entrez Gene 518540
UniGene Bt.63482
RefSeq NM_001098045
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC140506 DAAA02009993 DAAA02009994 DAAA02009995
GenPept AAI40507
RNA Seq Atlas 518540

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca