InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: BT.103203

Summary

InnateDB Gene

IDBG-629873.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BT.103203

Gene Name

synaptojanin-1

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000003063

Encoded Proteins

IDBP-681310

synaptojanin-1

IDBP-681315

synaptojanin-1

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000159082:
This gene encodes a phosphoinositide phosphatase that regulates levels of membrane phosphatidylinositol-4,5-bisphosphate. As such, expression of this enzyme may affect synaptic transmission and membrane trafficking. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:2109219-2196114

Strand

Forward strand

Band

Transcripts

ENSBTAT00000003985	ENSBTAP00000003985
ENSBTAT00000003984	ENSBTAP00000003984

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.

Predicted by orthology
Total	20 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
GO:0005515	protein binding
GO:0034595	phosphatidylinositol phosphate 5-phosphatase activity
GO:0042578	phosphoric ester hydrolase activity

Biological Process

GO:0006836	neurotransmitter transport
GO:0007612	learning
GO:0016082	synaptic vesicle priming
GO:0016191	synaptic vesicle uncoating
GO:0046488	phosphatidylinositol metabolic process
GO:0046855	inositol phosphate dephosphorylation
GO:0046856	phosphatidylinositol dephosphorylation
GO:0048488	synaptic vesicle endocytosis
GO:0048489	synaptic vesicle transport