InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: COX7A2

Summary

InnateDB Gene

IDBG-629888.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COX7A2

Gene Name

Cytochrome c oxidase subunit 7A2, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000005096

Encoded Proteins

IDBP-681312

cytochrome c oxidase subunit 7A2, mitochondrial precursor

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112695:
Cytochrome c oxidase, the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of three catalytic subunits encoded by mitochondrial genes, and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, while the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (liver isoform) of subunit VIIa, with this polypeptide being present in both muscle and non-muscle tissues. In addition to polypeptide 2, subunit VIIa includes polypeptide 1 (muscle isoform), which is present only in muscle tissues, and a related protein, which is present in all tissues. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4 and 14. [provided by RefSeq, Oct 2009]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:15041836-15046972

Strand

Reverse strand

Band

Transcripts

ENSBTAT00000006715

ENSBTAP00000006715

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.

Predicted by orthology
Total	7 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity
GO:0009055	electron carrier activity

Biological Process

GO:1902600

hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0005746	mitochondrial respiratory chain
GO:0016020	membrane
GO:0070062	extracellular vesicular exosome