Version 5.4
Bos taurus Gene: CNGA3
Summary
InnateDB Gene IDBG-629956.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CNGA3
Gene Name Cyclic nucleotide-gated cation channel alpha-3
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009834
Encoded Proteins
IDBP-681386
Cyclic nucleotide-gated cation channel alpha-3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144191:
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 11:3553257-3590989
Strand Forward strand
Band
Transcripts
ENSBTAT00000056449 ENSBTAP00000052464
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0005216 ion channel activity
GO:0005221 intracellular cyclic nucleotide activated cation channel activity
GO:0005222 intracellular cAMP activated cation channel activity
GO:0005223 intracellular cGMP activated cation channel activity
GO:0005249 voltage-gated potassium channel activity
GO:0005515 protein binding
GO:0030553 cGMP binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006812 cation transport
GO:0007601 visual perception
GO:0007603 phototransduction, visible light
GO:0042391 regulation of membrane potential
GO:0046549 retinal cone cell development
GO:0050896 response to stimulus
GO:0055085 transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0001750 photoreceptor outer segment
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:1902495 transmembrane transporter complex
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000144191
View Gene Order
ENSMUSG00000026114
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
KEGG
hsa04740
Olfactory transduction pathway
mmu04740
Olfactory transduction pathway
INOH
PID NCI
cone_pathway
Visual signal transduction: Cones
Cross-References
SwissProt Q29441
TrEMBL
UniProt Splice Variant
Entrez Gene 281701
UniGene Bt.109785 Bt.64967
RefSeq NM_174279 XM_005212282 XM_005212283 XM_005212284 XM_005212285 XM_005212286 XM_005212287
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL X76485 X89600
GenPept CAA54023 CAA61759
RNA Seq Atlas 281701

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca