InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Gene: Cnga3

Summary

InnateDB Gene

IDBG-145667.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cnga3

Gene Name

cyclic nucleotide gated channel alpha 3

Synonyms

CNG3

Species

Mus musculus

Ensembl Gene

ENSMUSG00000026114

Encoded Proteins

IDBP-145669

cyclic nucleotide gated channel alpha 3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000144191:
This gene encodes a member of the cyclic nucleotide-gated cation channel protein family which is required for normal vision and olfactory signal transduction. Mutations in this gene are associated with achromatopsia (rod monochromacy) and color blindness. Two alternatively spliced transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 1:37219261-37263383

Strand

Forward strand

Band

Transcripts

ENSMUST00000027288

ENSMUSP00000027288

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	1 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005221	intracellular cyclic nucleotide activated cation channel activity
GO:0005222	intracellular cAMP activated cation channel activity
GO:0005223	intracellular cGMP activated cation channel activity
GO:0005249	voltage-gated potassium channel activity
GO:0005515	protein binding
GO:0008022	protein C-terminus binding
GO:0030553	cGMP binding

Biological Process

GO:0006811	ion transport
GO:0006812	cation transport
GO:0007601	visual perception
GO:0007603	phototransduction, visible light
GO:0031960	response to corticosteroid
GO:0032026	response to magnesium ion
GO:0034220	ion transmembrane transport
GO:0042391	regulation of membrane potential
GO:0046549	retinal cone cell development
GO:0051591	response to cAMP
GO:0055085	transmembrane transport
GO:0071805	potassium ion transmembrane transport

Cellular Component

GO:0001750	photoreceptor outer segment
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane
GO:0030425	dendrite
GO:0042622	photoreceptor outer segment membrane
GO:0043025	neuronal cell body
GO:0043204	perikaryon
GO:1902495	transmembrane transporter complex

Orthologs

Species

Homo sapiens

Bos taurus

Gene ID

Gene Order

ENSG00000144191

View Gene Order

ENSBTAG00000009834

Not yet available

Pathways

NETPATH

REACTOME

KEGG

mmu04740

Olfactory transduction pathway

INOH

PID NCI

Pathway Predictions based on Human Orthology Data

NETPATH

REACTOME

KEGG

hsa04740

Olfactory transduction pathway

INOH

PID NCI

cone_pathway

Visual signal transduction: Cones

Cross-References

SwissProt

Q9JJZ8

TrEMBL

UniProt Splice Variant

Entrez Gene

12790

UniGene

Mm.214224

RefSeq

NM_009918 XM_006495639 XM_006495640 XM_006495641

OMIM

CCDS

CCDS14890

HPRD

IMGT

MGI ID

MGI:1341818

MGI Symbol

Cnga3

EMBL

AJ238239 AJ238240 AJ238241 AJ243933 BC035272 BC049145

GenPept

AAH35272 AAH49145 CAB42891 CAB89685

RNA Seq Atlas

12790