Version 5.4
Bos taurus Gene: PDS5B
Summary
InnateDB Gene IDBG-630075.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PDS5B
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000011597
Encoded Proteins
IDBP-681630
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000083642:
This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, May 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 12:28332887-28445729
Strand Reverse strand
Band
Transcripts
ENSBTAT00000015410 ENSBTAP00000015410
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 26 interaction(s) predicted by orthology.
Predicted by orthology
Total 26 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005488 binding
GO:0005515 protein binding
Biological Process
GO:0007064 mitotic sister chromatid cohesion
GO:0008285 negative regulation of cell proliferation
GO:0042127 regulation of cell proliferation
Cellular Component
GO:0000785 chromatin
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000083642
View Gene Order
ENSMUSG00000034021
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_150425
Resolution of Sister Chromatid Cohesion pathway
REACT_682
Mitotic Prometaphase pathway
REACT_150471
Separation of Sister Chromatids pathway
REACT_150421
Cohesin Loading onto Chromatin pathway
REACT_1932
Mitotic Telophase/Cytokinesis pathway
REACT_150266
Establishment of Sister Chromatid Cohesion pathway
REACT_899
S Phase pathway
REACT_115566
Cell Cycle pathway
REACT_910
M Phase pathway
REACT_1275
Mitotic Anaphase pathway
REACT_152
Cell Cycle, Mitotic pathway
REACT_150314
Mitotic Metaphase and Anaphase pathway
REACT_249770
Cell Cycle, Mitotic pathway
REACT_207679
Separation of Sister Chromatids pathway
REACT_198961
Resolution of Sister Chromatid Cohesion pathway
REACT_188804
Cell Cycle pathway
REACT_241408
M Phase pathway
REACT_250427
Mitotic Telophase/Cytokinesis pathway
REACT_199403
Mitotic Metaphase and Anaphase pathway
REACT_256756
Mitotic Prometaphase pathway
REACT_196634
Cohesin Loading onto Chromatin pathway
REACT_196614
Establishment of Sister Chromatid Cohesion pathway
REACT_202512
Mitotic Anaphase pathway
REACT_253623
S Phase pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N7G8
UniProt Splice Variant
Entrez Gene 533890
UniGene Bt.105174
RefSeq XM_002691755 XM_005194134 XM_005213745 XM_613447
HUGO HGNC:20418
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02033076
GenPept
RNA Seq Atlas 533890

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca