Version 5.4
Bos taurus Gene: STARD5
Summary
InnateDB Gene IDBG-630370.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STARD5
Gene Name StAR-related lipid transfer protein 5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010964
Encoded Proteins
IDBP-681818
StAR-related lipid transfer protein 5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000172345:
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD5 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 21:27608609-27617253
Strand Reverse strand
Band
Transcripts
ENSBTAT00000014559 ENSBTAP00000014559
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0008289 lipid binding
Biological Process
GO:0006810 transport
GO:0006869 lipid transport
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000172345
View Gene Order
ENSMUSG00000046027
View Gene Order
Pathways
NETPATH
REACTOME
REACT_211020
Pregnenolone biosynthesis pathway
REACT_219933
Metabolism of lipids and lipoproteins pathway
REACT_208375
Metabolism of steroid hormones and vitamin D pathway
REACT_219139
Metabolism pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_11038
Pregnenolone biosynthesis pathway
REACT_22258
Metabolism of lipids and lipoproteins pathway
REACT_11057
Metabolism of steroid hormones and vitamin D pathway
REACT_111217
Metabolism pathway
REACT_188937
Metabolism pathway
REACT_232291
Metabolism of lipids and lipoproteins pathway
REACT_223561
Pregnenolone biosynthesis pathway
REACT_220061
Metabolism of steroid hormones and vitamin D pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt A1A4M6
TrEMBL
UniProt Splice Variant
Entrez Gene 512369
UniGene
RefSeq NM_001080265 XM_005221877
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC126727
GenPept AAI26728
RNA Seq Atlas 512369

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca