Version 5.4
| Bos taurus Gene: SDHD | |||||||
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| Summary | |||||||
| InnateDB Gene | IDBG-630471.3 | ||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||
| Gene Symbol | SDHD | ||||||
| Gene Name | Succinate dehydrogenase | ||||||
| Synonyms | CII-4; CII4; cybS; QPs3 | ||||||
| Species | Bos taurus | ||||||
| Ensembl Gene | ENSBTAG00000016266 | ||||||
| Encoded Proteins |
succinate dehydrogenase
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| Protein Structure | |||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||
| Entrez Gene | |||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000204370:
This gene encodes a member of complex II of the respiratory chain, which is responsible for the oxidation of succinate. The encoded protein is one of two integral membrane proteins anchoring the complex to the matrix side of the mitochondrial inner membrane. Mutations in this gene are associated with the formation of tumors, including hereditary paraganglioma. Transmission of disease occurs almost exclusively through the paternal allele, suggesting that this locus may be maternally imprinted. There are pseudogenes for this gene on chromosomes 1, 2, 3, 7, and 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013] |
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| Gene Information | |||||||
| Type | Protein coding | ||||||
| Genomic Location | Chromosome 15:22722376-22733137 | ||||||
| Strand | Forward strand | ||||||
| Band | |||||||
| Transcripts |
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| Interactions | |||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||
| NETPATH | |||||||
| REACTOME |
Respiratory electron transport pathway
Citric acid cycle (TCA cycle) pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Metabolism pathway
The citric acid (TCA) cycle and respiratory electron transport pathway
Respiratory electron transport pathway
Metabolism pathway
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. pathway
Pyruvate metabolism and Citric Acid (TCA) cycle pathway
Citric acid cycle (TCA cycle) pathway
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| KEGG |
Citrate cycle (TCA cycle) pathway
Alzheimer's disease pathway
Oxidative phosphorylation pathway
Parkinson's disease pathway
Huntington's disease pathway
Oxidative phosphorylation pathway
Alzheimer's disease pathway
Citrate cycle (TCA cycle) pathway
Parkinson's disease pathway
Huntington's disease pathway
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| INOH | |||||||
| PID NCI | |||||||
| Cross-References | |||||||
| SwissProt | |||||||
| TrEMBL | B9W0B4 C0LQL2 V6F7N8 | ||||||
| UniProt Splice Variant | |||||||
| Entrez Gene | 281481 | ||||||
| UniGene | Bt.65279 | ||||||
| RefSeq | NM_174179 XM_005215802 | ||||||
| HUGO | |||||||
| OMIM | |||||||
| CCDS | |||||||
| HPRD | |||||||
| IMGT | |||||||
| EMBL | FJ621574 FJ752761 GJ062397 | ||||||
| GenPept | ACM69045 ACN71230 DAA22358 | ||||||
| RNA Seq Atlas | 281481 | ||||||