Version 5.4
Bos taurus Gene: SLC6A15
Summary
InnateDB Gene IDBG-630502.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC6A15
Gene Name Sodium-dependent neutral amino acid transporter B(0)AT2
Synonyms NTT73
Species Bos taurus
Ensembl Gene ENSBTAG00000018432
Encoded Proteins
IDBP-681962
Sodium-dependent neutral amino acid transporter B(0)AT2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000072041:
This gene encodes a member of the solute carrier family 6 protein family which transports neutral amino acids. The encoded protein is thought to play a role in neuronal amino acid transport (PMID: 16185194) and may be associated with major depression (PMID: 21521612). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012]
Gene Information
Type Protein coding
Genomic Location Chromosome 5:14572186-14604741
Strand Reverse strand
Band
Transcripts
ENSBTAT00000024524 ENSBTAP00000024524
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005298 proline:sodium symporter activity
GO:0005328 neurotransmitter:sodium symporter activity
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0006814 sodium ion transport
GO:0006836 neurotransmitter transport
GO:0006865 amino acid transport
GO:0015804 neutral amino acid transport
GO:0015820 leucine transport
GO:0015824 proline transport
GO:0035524 proline transmembrane transport
GO:0055085 transmembrane transport
Cellular Component
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000072041
View Gene Order
ENSMUSG00000019894
View Gene Order
Pathways
NETPATH
REACTOME
REACT_222460
SLC-mediated transmembrane transport pathway
REACT_223103
Transmembrane transport of small molecules pathway
REACT_203377
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_202360
Amino acid transport across the plasma membrane pathway
REACT_206645
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_212003
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_20506
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_19305
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_13796
Amino acid transport across the plasma membrane pathway
REACT_19397
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_19118
SLC-mediated transmembrane transport pathway
REACT_217615
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds pathway
REACT_247550
SLC-mediated transmembrane transport pathway
REACT_251788
Transport of inorganic cations/anions and amino acids/oligopeptides pathway
REACT_253228
Na+/Cl- dependent neurotransmitter transporters pathway
REACT_253400
Transmembrane transport of small molecules pathway
REACT_230460
Amino acid transport across the plasma membrane pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q9XS59
TrEMBL
UniProt Splice Variant
Entrez Gene 281952
UniGene Bt.4547
RefSeq NM_181023 XM_005206043
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AB020854
GenPept BAA77223
RNA Seq Atlas 281952

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca