Version 5.4
Bos taurus Gene: SASH3
Summary
InnateDB Gene IDBG-630574.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SASH3
Gene Name SAM and SH3 domain-containing protein 3
Synonyms HXCXORF9
Species Bos taurus
Ensembl Gene ENSBTAG00000002041
Encoded Proteins
IDBP-682046
SAM and SH3 domain-containing protein 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000122122:
The protein encoded by this gene contains a Src homology-3 (SH3) domain and a sterile alpha motif (SAM), both of which are found in proteins involved in cell signaling. This protein may function as a signaling adapter protein in lymphocytes.[provided by RefSeq, Sep 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome X:13681411-13695769
Strand Forward strand
Band
Transcripts
ENSBTAT00000002645 ENSBTAP00000002645
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0002639 positive regulation of immunoglobulin production
GO:0002726 positive regulation of T cell cytokine production
GO:0002821 positive regulation of adaptive immune response
GO:0030890 positive regulation of B cell proliferation
GO:0032729 positive regulation of interferon-gamma production
GO:0032733 positive regulation of interleukin-10 production
GO:0032743 positive regulation of interleukin-2 production
GO:0032753 positive regulation of interleukin-4 production
GO:0032760 positive regulation of tumor necrosis factor production
GO:0042102 positive regulation of T cell proliferation
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
GO:0046622 positive regulation of organ growth
GO:0048873 homeostasis of number of cells within a tissue
GO:0051251 positive regulation of lymphocyte activation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000122122
View Gene Order
ENSMUSG00000031101
View Gene Order
Cross-References
SwissProt A0JN71
TrEMBL
UniProt Splice Variant
Entrez Gene 534137
UniGene Bt.54950
RefSeq NM_001077998 XM_005227492
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL AAFC03003066 BC126545
GenPept AAI26546
RNA Seq Atlas 534137

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca