Version 5.4
Bos taurus Gene: BT.106425
Summary
InnateDB Gene IDBG-630680.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.106425
Gene Name 5-hydroxytryptamine receptor 3A precursor
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010791
Encoded Proteins
IDBP-682156
Uncharacterized protein
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000166736:
The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:24838867-24851695
Strand Forward strand
Band
Transcripts
ENSBTAT00000014292 ENSBTAP00000014292
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004993 serotonin receptor activity
GO:0005230 extracellular ligand-gated ion channel activity
GO:0015276 ligand-gated ion channel activity
GO:0051378 serotonin binding
Biological Process
GO:0006810 transport
GO:0006811 ion transport
GO:0007210 serotonin receptor signaling pathway
GO:0034220 ion transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000166736
View Gene Order
ENSMUSG00000032269
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_25387
Ligand-gated ion channel transport pathway
REACT_15518
Transmembrane transport of small molecules pathway
REACT_25300
Ion channel transport pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL F1N4Y2
UniProt Splice Variant
Entrez Gene 617674
UniGene Bt.106425
RefSeq NM_001193169 XM_005215869
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02040317 GJ062397
GenPept DAA22407
RNA Seq Atlas 617674

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca