Version 5.4
Bos taurus Gene: CER1
Summary
InnateDB Gene IDBG-630780.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CER1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000020140
Encoded Proteins
IDBP-682262
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000147869:
This gene encodes a cytokine member of the cysteine knot superfamily, characterized by nine conserved cysteines and a cysteine knot region. The cerberus-related cytokines, together with Dan and DRM/Gremlin, represent a group of bone morphogenetic protein (BMP) antagonists that can bind directly to BMPs and inhibit their activity. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:29522480-29525223
Strand Forward strand
Band
Transcripts
ENSBTAT00000026824 ENSBTAP00000026824
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016015 morphogen activity
GO:0036122 BMP binding
GO:0042803 protein homodimerization activity
Biological Process
GO:0001657 ureteric bud development
GO:0003419 growth plate cartilage chondrocyte proliferation
GO:0007369 gastrulation
GO:0007399 nervous system development
GO:0008285 negative regulation of cell proliferation
GO:0009948 anterior/posterior axis specification
GO:0009952 anterior/posterior pattern specification
GO:0023019 signal transduction involved in regulation of gene expression
GO:0030282 bone mineralization
GO:0030514 negative regulation of BMP signaling pathway
GO:0032926 negative regulation of activin receptor signaling pathway
GO:0035582 sequestering of BMP in extracellular matrix
GO:0042074 cell migration involved in gastrulation
GO:0048263 determination of dorsal identity
GO:2000381 negative regulation of mesoderm development
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000147869
View Gene Order
ENSMUSG00000038192
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_12034
Signaling by BMP pathway
REACT_111059
Regulation of signaling by NODAL pathway
REACT_111057
Signaling by NODAL pathway
REACT_111045
Developmental Biology pathway
REACT_111102
Signal Transduction pathway
REACT_220505
Signaling by BMP pathway
REACT_220645
Signaling by NODAL pathway
REACT_199125
Regulation of signaling by NODAL pathway
REACT_188576
Developmental Biology pathway
REACT_188257
Signal Transduction pathway
KEGG
hsa04310
Wnt signaling pathway pathway
mmu04310
Wnt signaling pathway pathway
INOH
PID NCI
bmppathway
BMP receptor signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq XM_002689577 XM_584735
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca