Bos taurus Gene: IL1RL2 | |||||||||||||
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Summary | |||||||||||||
InnateDB Gene | IDBG-630827.3 | ||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||
Gene Symbol | IL1RL2 | ||||||||||||
Gene Name | interleukin-1 receptor-like 2 precursor | ||||||||||||
Synonyms | |||||||||||||
Species | Bos taurus | ||||||||||||
Ensembl Gene | ENSBTAG00000005704 | ||||||||||||
Encoded Proteins |
interleukin 1 receptor-like 2
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Protein Structure | |||||||||||||
Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||
InnateDB Annotation from Orthologs | |||||||||||||
Summary |
[Homo sapiens] IL1RL2 binds members of the interleukin (IL)-1 family of cytokines that includes IL1F6, IL1F8 and IL1F9. Binding of these ligands to IL1RL2 plays a critical role in the interface between innate and adaptive immunity, leading to the stimulation of dendritic and T helper cell responses. (Demonstrated in murine model)
[Mus musculus] Il1rl2 binds members of the interleukin (IL)-1 family of cytokines that includes Il1f6, Il1f8 and Il1f9. Binding of these ligands to Il1rl2 plays a critical role in the interface between innate and adaptive immunity, leading to the stimulation of dendritic and T helper cell responses.
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Entrez Gene | |||||||||||||
Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115598:
The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||
Type | Protein coding | ||||||||||||
Genomic Location | Chromosome 11:7020020-7045388 | ||||||||||||
Strand | Forward strand | ||||||||||||
Band | |||||||||||||
Transcripts |
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Interactions | |||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||
Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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Cross-References | |||||||||||||
SwissProt | |||||||||||||
TrEMBL | |||||||||||||
UniProt Splice Variant | |||||||||||||
Entrez Gene | |||||||||||||
UniGene | Bt.61798 | ||||||||||||
RefSeq | NM_001192554 XM_005212446 | ||||||||||||
HUGO | |||||||||||||
OMIM | |||||||||||||
CCDS | |||||||||||||
HPRD | |||||||||||||
IMGT | |||||||||||||
EMBL | |||||||||||||
GenPept | |||||||||||||
RNA Seq Atlas | |||||||||||||