Version 5.4
Bos taurus Gene: GOPC
Summary
InnateDB Gene IDBG-630837.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GOPC
Gene Name Golgi-associated PDZ and coiled-coil motif-containing protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000016046
Encoded Proteins
IDBP-682336
golgi-associated PDZ and coiled-coil motif containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 16878151
[Homo sapiens] GOPC (cystic fibrosis transmembrane regulator-associated ligand) interacts with human papillomavirus type 16 E6 protein to promote E6-associated protein (E6AP)-mediated ubiquitination and proteasomal degradation.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000047932:
This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:33628854-33665784
Strand Forward strand
Band
Transcripts
ENSBTAT00000021350 ENSBTAP00000021350
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0005515 protein binding
GO:0044325 ion channel binding
Biological Process
GO:0007289 spermatid nucleus differentiation
GO:0050790 regulation of catalytic activity
GO:0051260 protein homooligomerization
Cellular Component
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0043234 protein complex
GO:0045202 synapse
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000047932
View Gene Order
ENSMUSG00000019861
View Gene Order
Cross-References
SwissProt
TrEMBL E1BAX1
UniProt Splice Variant
Entrez Gene 541186
UniGene Bt.91807
RefSeq NM_001206157
HUGO HGNC:17643
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025761
GenPept
RNA Seq Atlas 541186

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca