Version 5.4
Mus musculus Gene: Gopc
Summary
InnateDB Gene IDBG-150968.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Gopc
Gene Name golgi associated PDZ and coiled-coil motif containing
Synonyms 2210402P09Rik; AI844555; CAL; FIG; GOPC1; PIST
Species Mus musculus
Ensembl Gene ENSMUSG00000019861
Encoded Proteins
IDBP-150970
golgi associated PDZ and coiled-coil motif containing
IDBP-270803
golgi associated PDZ and coiled-coil motif containing
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
InnateDB Annotation from Orthologs
Summary
PMID 16878151
[Homo sapiens] GOPC (cystic fibrosis transmembrane regulator-associated ligand) interacts with human papillomavirus type 16 E6 protein to promote E6-associated protein (E6AP)-mediated ubiquitination and proteasomal degradation.
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000047932:
This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 10:52337024-52382124
Strand Reverse strand
Band B3
Transcripts
ENSMUST00000020008 ENSMUSP00000020008
ENSMUST00000105475 ENSMUSP00000101115
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 28 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 28 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005083 small GTPase regulator activity
GO:0005109 frizzled binding
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019905 syntaxin binding
GO:0042803 protein homodimerization activity
GO:0044325 ion channel binding
Biological Process
GO:0006914 autophagy
GO:0007289 spermatid nucleus differentiation
GO:0015031 protein transport
GO:0050790 regulation of catalytic activity
GO:0051260 protein homooligomerization
Cellular Component
GO:0000139 Golgi membrane
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0030054 cell junction
GO:0030140 trans-Golgi network transport vesicle
GO:0030425 dendrite
GO:0043234 protein complex
GO:0045202 synapse
GO:0045211 postsynaptic membrane
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000047932
View Gene Order
ENSBTAG00000016046
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Mm.396961
RefSeq NM_001199272 NM_053187
OMIM
CCDS CCDS35898
HPRD
IMGT
MGI ID
MGI Symbol
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca