Version 5.4
Bos taurus Gene: ZMIZ1
Summary
InnateDB Gene IDBG-630893.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ZMIZ1
Gene Name Uncharacterized protein
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000019313
Encoded Proteins
IDBP-682437
zinc finger, MIZ-type containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108175:
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 28:35032455-35142181
Strand Forward strand
Band
Transcripts
ENSBTAT00000025717 ENSBTAP00000025717
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0007296 vitellogenesis
GO:0007569 cell aging
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048146 positive regulation of fibroblast proliferation
GO:0048589 developmental growth
GO:0048844 artery morphogenesis
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000108175
View Gene Order
ENSMUSG00000007817
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
ar_pathway
Coregulation of Androgen receptor activity
Cross-References
SwissProt
TrEMBL F1MP12
UniProt Splice Variant
Entrez Gene 616740
UniGene Bt.110006 Bt.46594
RefSeq XM_002698888 XM_005226519 XM_005226520
HUGO HGNC:16493
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02061988 DAAA02061989 DAAA02061990 DAAA02061991
GenPept
RNA Seq Atlas 616740

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca