Version 5.4
Mus musculus Gene: Zmiz1
Summary
InnateDB Gene IDBG-138696.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Zmiz1
Gene Name zinc finger, MIZ-type containing 1
Synonyms
Species Mus musculus
Ensembl Gene ENSMUSG00000007817
Encoded Proteins
IDBP-138698
zinc finger, MIZ-type containing 1
IDBP-535962
zinc finger, MIZ-type containing 1
IDBP-532891
zinc finger, MIZ-type containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000108175:
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 14:25459185-25666743
Strand Forward strand
Band A3
Transcripts
ENSMUST00000007961 ENSMUSP00000007961
ENSMUST00000161766
ENSMUST00000162645 ENSMUSP00000124863
ENSMUST00000159766
ENSMUST00000160680
ENSMUST00000160190
ENSMUST00000160229 ENSMUSP00000124820
ENSMUST00000162546
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0008270 zinc ion binding
Biological Process
GO:0001570 vasculogenesis
GO:0001701 in utero embryonic development
GO:0003007 heart morphogenesis
GO:0006351 transcription, DNA-templated
GO:0007296 vitellogenesis
GO:0007569 cell aging
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048146 positive regulation of fibroblast proliferation
GO:0048589 developmental growth
GO:0048844 artery morphogenesis
Cellular Component
GO:0005737 cytoplasm
GO:0016607 nuclear speck
Orthologs
Species
Homo sapiens
Bos taurus
Gene ID
Gene Order
ENSG00000108175
View Gene Order
ENSBTAG00000019313
Not yet available
Pathway Predictions based on Human Orthology Data
NETPATH
NetPath_2
AndrogenReceptor pathway
REACTOME
KEGG
INOH
PID NCI
ar_pathway
Coregulation of Androgen receptor activity
Cross-References
SwissProt Q6P1E1
TrEMBL E0CX95
UniProt Splice Variant
Entrez Gene 328365
UniGene Mm.227484 Mm.489608
RefSeq NM_183208 XM_006519133 XM_006519135
OMIM
CCDS CCDS26873
HPRD
IMGT
MGI ID MGI:3040693
MGI Symbol Zmiz1
EMBL AC154455 AC154759 AC157650 AK054366 BC057691 BC058646 BC065120
GenPept AAH57691 AAH58646 AAH65120 BAC35753
RNA Seq Atlas 328365

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca