Bos taurus Gene: CCL2
InnateDB Gene IDBG-630954.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CCL2
Gene Name C-C motif chemokine 2
Synonyms MCP-1; MCP-1A; MCP1; MCP1A; SCYA2;
Species Bos taurus
Ensembl Gene ENSBTAG00000037811
Encoded Proteins
C-C motif chemokine 2
Protein Structure
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 19:16232968-16234839
Strand Reverse strand
ENSBTAT00000013146 ENSBTAP00000013146
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0001664 G-protein coupled receptor binding
GO:0005125 cytokine activity
GO:0005515 protein binding
GO:0008009 chemokine activity
GO:0031727 CCR2 chemokine receptor binding
Biological Process
GO:0000165 MAPK cascade
GO:0002548 monocyte chemotaxis
GO:0006935 chemotaxis
GO:0006954 inflammatory response
GO:0006955 immune response
GO:0007010 cytoskeleton organization
GO:0008360 regulation of cell shape
GO:0009611 response to wounding
GO:0009617 response to bacterium
GO:0010574 regulation of vascular endothelial growth factor production
GO:0010759 positive regulation of macrophage chemotaxis
GO:0016525 negative regulation of angiogenesis
GO:0019221 cytokine-mediated signaling pathway
GO:0031663 lipopolysaccharide-mediated signaling pathway
GO:0034351 negative regulation of glial cell apoptotic process
GO:0035684 helper T cell extravasation
GO:0043491 protein kinase B signaling
GO:0043524 negative regulation of neuron apoptotic process
GO:0043615 astrocyte cell migration
GO:0044344 cellular response to fibroblast growth factor stimulus
GO:0048246 macrophage chemotaxis
GO:0050870 positive regulation of T cell activation
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process
GO:0071222 cellular response to lipopolysaccharide
GO:0071346 cellular response to interferon-gamma
GO:0071347 cellular response to interleukin-1
GO:0071356 cellular response to tumor necrosis factor
GO:0071407 cellular response to organic cyclic compound
GO:0090265 positive regulation of immune complex clearance by monocytes and macrophages
GO:0090280 positive regulation of calcium ion import
GO:2000427 positive regulation of apoptotic cell clearance
GO:2000502 negative regulation of natural killer cell chemotaxis
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
No orthologs found for this gene
PERK regulates gene expression pathway
Peptide ligand-binding receptors pathway
Signaling by GPCR pathway
ATF4 activates genes pathway
Signal Transduction pathway
Metabolism of proteins pathway
GPCR ligand binding pathway
Class A/1 (Rhodopsin-like receptors) pathway
Unfolded Protein Response (UPR) pathway
Chemokine receptors bind chemokines pathway
SwissProt P28291
UniProt Splice Variant
Entrez Gene 281043
UniGene Bt.2408
RefSeq NM_174006
EMBL EU276059 L32659 M84602
GenPept AAA30651 AAA60956 ABX72057
ImmGen CCL2 (murine)
RNA Seq Atlas 281043
Transcript Frequencies
Tag Count based mRNA-Abundances across 87 different Tissues (TPM).

Based on Data from Bovine Gene Atlas

Tag Count based mRNA-Abundances across 87 different Tissues (TPM)

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