InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: CCL2

Summary

InnateDB Gene

IDBG-630954.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CCL2

Gene Name

C-C motif chemokine 2

Synonyms

MCP-1; MCP-1A; MCP1; MCP1A; SCYA2

Species

Bos taurus

Ensembl Gene

ENSBTAG00000037811

Encoded Proteins

C-C motif chemokine 2

Protein Structure

Useful resources

Entrez Gene

Summary

Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.

Gene Information

Type

Protein coding

Genomic Location

Chromosome 19:16232968-16234839

Strand

Reverse strand

Band

Transcripts

ENSBTAP00000013146

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001664	G-protein coupled receptor binding
GO:0005125	cytokine activity
GO:0005515	protein binding
GO:0008009	chemokine activity
GO:0031727	CCR2 chemokine receptor binding

Biological Process

GO:0000165	MAPK cascade
GO:0002548	monocyte chemotaxis
GO:0006935	chemotaxis
GO:0006954	inflammatory response
GO:0006955	immune response
GO:0007010	cytoskeleton organization
GO:0008360	regulation of cell shape
GO:0009611	response to wounding
GO:0009617	response to bacterium
GO:0010574	regulation of vascular endothelial growth factor production
GO:0010759	positive regulation of macrophage chemotaxis
GO:0016525	negative regulation of angiogenesis
GO:0019221	cytokine-mediated signaling pathway
GO:0031663	lipopolysaccharide-mediated signaling pathway
GO:0034351	negative regulation of glial cell apoptotic process
GO:0035684	helper T cell extravasation
GO:0043491	protein kinase B signaling
GO:0043524	negative regulation of neuron apoptotic process
GO:0043615	astrocyte cell migration
GO:0044344	cellular response to fibroblast growth factor stimulus
GO:0048246	macrophage chemotaxis
GO:0050870	positive regulation of T cell activation
GO:0051770	positive regulation of nitric-oxide synthase biosynthetic process
GO:0071222	cellular response to lipopolysaccharide
GO:0071346	cellular response to interferon-gamma
GO:0071347	cellular response to interleukin-1
GO:0071356	cellular response to tumor necrosis factor
GO:0071407	cellular response to organic cyclic compound
GO:0090265	positive regulation of immune complex clearance by monocytes and macrophages
GO:0090280	positive regulation of calcium ion import
GO:2000427	positive regulation of apoptotic cell clearance
GO:2000502	negative regulation of natural killer cell chemotaxis