Version 5.4
Bos taurus Gene: PHF6
Summary
InnateDB Gene IDBG-630973.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PHF6
Gene Name PHD finger protein 6
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000015196
Encoded Proteins
IDBP-682468
PHD finger protein 6
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000156531:
This gene is a member of the plant homeodomain (PHD)-like finger (PHF) family. It encodes a protein with two PHD-type zinc finger domains, indicating a potential role in transcriptional regulation, that localizes to the nucleolus. Mutations affecting the coding region of this gene or the splicing of the transcript have been associated with Borjeson-Forssman-Lehmann syndrome (BFLS), a disorder characterized by mental retardation, epilepsy, hypogonadism, hypometabolism, obesity, swelling of subcutaneous tissue of the face, narrow palpebral fissures, and large ears. Alternate splicing results in multiple transcript variants, encoding different isoforms. [provided by RefSeq, Jun 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome X:18048862-18085914
Strand Forward strand
Band
Transcripts
ENSBTAT00000020218 ENSBTAP00000020218
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.
Predicted by orthology
Total 4 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0015631 tubulin binding
GO:0019899 enzyme binding
GO:0042393 histone binding
GO:0042826 histone deacetylase binding
GO:0043021 ribonucleoprotein complex binding
GO:0044822 poly(A) RNA binding
GO:0051219 phosphoprotein binding
GO:0097110 scaffold protein binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000156531
View Gene Order
ENSMUSG00000025626
View Gene Order
Cross-References
SwissProt
TrEMBL G3X763
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq
HUGO HGNC:18145
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02067572 DAAA02067573 DAAA02067574
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca