Version 5.4
Bos taurus Gene: GUCA1B
Summary
InnateDB Gene IDBG-631051.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GUCA1B
Gene Name guanylyl cyclase-activating protein 2
Synonyms GCAP2
Species Bos taurus
Ensembl Gene ENSBTAG00000012439
Encoded Proteins
IDBP-682550
guanylyl cyclase-activating protein 2
IDBP-682552
guanylyl cyclase-activating protein 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112599:
The protein encoded by this gene is a calcium-binding protein that activates photoreceptor guanylate cyclases. This gene may have arisen due to a gene duplication event since there is a highly similar gene clustered with it on chromosome 6. Mutations in this gene can cause a form of retinitis pigmentosa. [provided by RefSeq, Nov 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 23:15910249-15921069
Strand Reverse strand
Band
Transcripts
ENSBTAT00000036072 ENSBTAP00000035936
ENSBTAT00000016509 ENSBTAP00000016509
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005509 calcium ion binding
GO:0008048 calcium sensitive guanylate cyclase activator activity
GO:0030249 guanylate cyclase regulator activity
GO:0046872 metal ion binding
Biological Process
GO:0007601 visual perception
GO:0007602 phototransduction
GO:0031282 regulation of guanylate cyclase activity
GO:0031284 positive regulation of guanylate cyclase activity
Cellular Component
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000112599
View Gene Order
ENSMUSG00000023979
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_111102
Signal Transduction pathway
REACT_160102
Diseases associated with visual transduction pathway
REACT_160125
Visual phototransduction pathway
REACT_163722
The phototransduction cascade pathway
REACT_163919
Inactivation, recovery and regulation of the phototransduction cascade pathway
REACT_116125
Disease pathway
REACT_189085
Disease pathway
REACT_188260
Visual phototransduction pathway
REACT_188266
Inactivation, recovery and regulation of the phototransduction cascade pathway
REACT_188265
The phototransduction cascade pathway
REACT_188257
Signal Transduction pathway
REACT_188255
Diseases associated with visual transduction pathway
KEGG
hsa04740
Olfactory transduction pathway
hsa04744
Phototransduction pathway
mmu04740
Olfactory transduction pathway
mmu04744
Phototransduction pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1BJY0
UniProt Splice Variant
Entrez Gene 286851
UniGene Bt.520
RefSeq NM_174786
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02055068
GenPept
RNA Seq Atlas 286851

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca