Version 5.4
Bos taurus Gene: TMPRSS4
Summary
InnateDB Gene IDBG-631207.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMPRSS4
Gene Name transmembrane protease serine 4
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000021518
Encoded Proteins
IDBP-682731
transmembrane protease serine 4
IDBP-682734
transmembrane protease serine 4
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000137648:
This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 15:29193486-29233495
Strand Forward strand
Band
Transcripts
ENSBTAT00000055576 ENSBTAP00000051578
ENSBTAT00000028678 ENSBTAP00000028678
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
GO:0005044 scavenger receptor activity
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0008236 serine-type peptidase activity
GO:0016787 hydrolase activity
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000137648
View Gene Order
ENSMUSG00000032091
View Gene Order
Cross-References
SwissProt
TrEMBL A6QPX2
UniProt Splice Variant
Entrez Gene 513343
UniGene Bt.42039
RefSeq XM_005215825 NM_001101973 XM_005215824
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC149533 DAAA02040400 DAAA02040401 DAAA02040402 DAAA02040403
GenPept AAI49534
RNA Seq Atlas 513343

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca