Version 5.4
| Bos taurus Gene: DOK1 | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-631228.3 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | DOK1 | ||||||||
| Gene Name | docking protein 1 | ||||||||
| Synonyms | |||||||||
| Species | Bos taurus | ||||||||
| Ensembl Gene | ENSBTAG00000018579 | ||||||||
| Encoded Proteins |
docking protein 1
docking protein 1
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| Protein Structure | |||||||||
| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000115325:
The protein encoded by this gene is part of a signal transduction pathway downstream of receptor tyrosine kinases. The encoded protein is a scaffold protein that helps form a platform for the assembly of multiprotein signaling complexes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 11:10068212-10071090 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | |||||||||
| Transcripts |
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| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 43 interaction(s) predicted by orthology.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
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Species
Homo sapiens
Mus musculus
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Gene ID
Gene Order
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| Pathway Predictions based on Human Orthology Data | |||||||||
| NETPATH |
EGFR1 pathway
KitReceptor pathway
TNFalpha pathway
TCR pathway
BCR pathway
IL1 pathway
IL3 pathway
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| REACTOME |
Signal attenuation pathway
IRS activation pathway
PI3K Cascade pathway
Signaling by Insulin receptor pathway
IRS-related events triggered by IGF1R pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
Signal Transduction pathway
IRS-mediated signalling pathway
Insulin receptor signalling cascade pathway
IRS-related events pathway
IGF1R signaling cascade pathway
Signaling by Insulin receptor pathway
Insulin receptor signalling cascade pathway
IRS-related events triggered by IGF1R pathway
IGF1R signaling cascade pathway
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) pathway
PI3K Cascade pathway
IRS activation pathway
IRS-related events pathway
IRS-mediated signalling pathway
Signal Transduction pathway
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| KEGG | |||||||||
| INOH | |||||||||
| PID NCI |
Signaling events mediated by PTP1B
BCR signaling pathway
Signaling events mediated by Stem cell factor receptor (c-Kit)
Signaling events regulated by Ret tyrosine kinase
Fc-epsilon receptor I signaling in mast cells
PDGFR-beta signaling pathway
Insulin Pathway
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| Cross-References | |||||||||
| SwissProt | |||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | |||||||||
| UniGene | Bt.26529 | ||||||||
| RefSeq | NM_001024543 | ||||||||
| HUGO | |||||||||
| OMIM | |||||||||
| CCDS | |||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | |||||||||
| GenPept | |||||||||
| RNA Seq Atlas | |||||||||