Version 5.4
Bos taurus Gene: BT.95322
Summary
InnateDB Gene IDBG-631242.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BT.95322
Gene Name myristoylated alanine-rich C-kinase substrate
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000002082
Encoded Proteins
IDBP-682753
myristoylated alanine-rich C-kinase substrate
IDBP-682760
myristoylated alanine-rich C-kinase substrate
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog null:
The protein encoded by this gene is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:37022764-37026932
Strand Reverse strand
Band
Transcripts
ENSBTAT00000002691 ENSBTAP00000002691
ENSBTAT00000052599 ENSBTAP00000052045
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005080 protein kinase C binding
GO:0005515 protein binding
GO:0005516 calmodulin binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005938 cell cortex
GO:0016020 membrane
GO:0042585 germinal vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
null
View Gene Order
ENSMUSG00000069662
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_217323
Integration of energy metabolism pathway
REACT_247495
Acetylcholine regulates insulin secretion pathway
REACT_188937
Metabolism pathway
REACT_263148
Regulation of insulin secretion pathway
KEGG
mmu04666
Fc gamma R-mediated phagocytosis pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL E1B916
UniProt Splice Variant
Entrez Gene 613548
UniGene Bt.101114
RefSeq NM_001076276
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02025851
GenPept
RNA Seq Atlas 613548

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca