Bos taurus Gene: ADCY7
Summary
InnateDB Gene IDBG-631601.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADCY7
Gene Name Adenylate cyclase type 7
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000006208
Encoded Proteins
adenylate cyclase type 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000121281:
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. [provided by RefSeq, Jul 2008]
This gene encodes a membrane-bound adenylate cyclase that catalyses the formation of cyclic AMP from ATP and is inhibitable by calcium. The product of this gene is a member of the adenylyl cyclase class-4/guanylyl cyclase enzyme family that is characterized by the presence of twelve membrane-spanning domains in its sequences. Several transcript variants have been observed for this gene, but the full-length natures of only two have been determined so far. [provided by RefSeq, Oct 2013]
Gene Information
Type Protein coding
Genomic Location Chromosome 18:18745674-18809260
Strand Forward strand
Band
Transcripts
ENSBTAT00000008153 ENSBTAP00000008153
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 5 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0004016 adenylate cyclase activity
GO:0005524 ATP binding
GO:0016829 lyase activity
GO:0016849 phosphorus-oxygen lyase activity
GO:0046872 metal ion binding
Biological Process
GO:0006171 cAMP biosynthetic process
GO:0009190 cyclic nucleotide biosynthetic process
GO:0030819 positive regulation of cAMP biosynthetic process
GO:0035556 intracellular signal transduction
GO:0071361 cellular response to ethanol
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Pathways
NETPATH
REACTOME
DAP12 interactions pathway
Aquaporin-mediated transport pathway
Signaling by EGFR pathway
Inhibition of adenylate cyclase pathway pathway
PLCG1 events in ERBB2 signaling pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
GABA B receptor activation pathway
PKA-mediated phosphorylation of CREB pathway
Signaling by GPCR pathway
Signaling by PDGF pathway
Calmodulin induced events pathway
DAG and IP3 signaling pathway
Adenylate cyclase inhibitory pathway pathway
G alpha (s) signalling events pathway
PLC-gamma1 signalling pathway
Signaling by FGFR pathway
GABA receptor activation pathway
Activation of GABAB receptors pathway
Immune System pathway
Integration of energy metabolism pathway
Transmission across Chemical Synapses pathway
EGFR interacts with phospholipase C-gamma pathway
Transmembrane transport of small molecules pathway
Adenylate cyclase activating pathway pathway
G alpha (i) signalling events pathway
Signaling by ERBB2 pathway
Signal Transduction pathway
Signaling by EGFR in Cancer pathway
Hedgehog 'off' state pathway
G-protein mediated events pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
NGF signalling via TRKA from the plasma membrane pathway
GPCR downstream signaling pathway
PLC beta mediated events pathway
Downstream signaling of activated FGFR pathway
Neuronal System pathway
Metabolism pathway
Signalling by NGF pathway
PKA activation pathway
Signaling by Hedgehog pathway
Phospholipase C-mediated cascade pathway
PKA activation in glucagon signalling pathway
Downstream signal transduction pathway
Opioid Signalling pathway
Glucagon signaling in metabolic regulation pathway
Innate Immune System pathway
Ca-dependent events pathway
CaM pathway pathway
DAP12 signaling pathway
Disease pathway
Signaling by FGFR in disease pathway
G alpha (z) signalling events pathway
KEGG
INOH
PID NCI
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
PKA activation pathway
PKA-mediated phosphorylation of CREB pathway
Calmodulin induced events pathway
CaM pathway pathway
DAG and IP3 signaling pathway
DAP12 signaling pathway
DAP12 interactions pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
PLC-gamma1 signalling pathway
EGFR interacts with phospholipase C-gamma pathway
Signaling by EGFR pathway
G alpha (i) signalling events pathway
G alpha (s) signalling events pathway
G alpha (z) signalling events pathway
Adenylate cyclase activating pathway pathway
Adenylate cyclase inhibitory pathway pathway
PLC beta mediated events pathway
Opioid Signalling pathway
PLCG1 events in ERBB2 signaling pathway
Signaling by ERBB2 pathway
Phospholipase C-mediated cascade pathway
Signaling by FGFR pathway
Downstream signal transduction pathway
Signaling by PDGF pathway
GABA B receptor activation pathway
PKA activation in glucagon signalling pathway
Glucagon signaling in metabolic regulation pathway
Integration of energy metabolism pathway
Signaling by FGFR in disease pathway
Transmembrane transport of small molecules pathway
Signalling by NGF pathway
Signaling by Hedgehog pathway
Signaling by EGFR in Cancer pathway
Downstream signaling of activated FGFR pathway
Neuronal System pathway
Signaling by GPCR pathway
Innate Immune System pathway
GABA receptor activation pathway
Activation of GABAB receptors pathway
Signal Transduction pathway
GPCR downstream signaling pathway
Hedgehog 'off' state pathway
G-protein mediated events pathway
Immune System pathway
NGF signalling via TRKA from the plasma membrane pathway
Transmission across Chemical Synapses pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Metabolism pathway
Inhibition of adenylate cyclase pathway pathway
Ca-dependent events pathway
Aquaporin-mediated transport pathway
Disease pathway
G alpha (s) signalling events pathway
Innate Immune System pathway
Signaling by ERBB2 pathway
PLCG1 events in ERBB2 signaling pathway
GPCR downstream signaling pathway
Disease pathway
Signaling by GPCR pathway
Glucagon signaling in metabolic regulation pathway
Hedgehog 'off' state pathway
Integration of energy metabolism pathway
Ca-dependent events pathway
Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell pathway
Signaling by FGFR in disease pathway
PLC-gamma1 signalling pathway
PKA-mediated phosphorylation of CREB pathway
Adenylate cyclase inhibitory pathway pathway
Metabolism pathway
PKA activation in glucagon signalling pathway
Immune System pathway
EGFR interacts with phospholipase C-gamma pathway
Activation of GABAB receptors pathway
Aquaporin-mediated transport pathway
Downstream signal transduction pathway
Downstream signaling of activated FGFR pathway
CaM pathway pathway
Inhibition of adenylate cyclase pathway pathway
Vasopressin regulates renal water homeostasis via Aquaporins pathway
Signaling by EGFR pathway
GABA B receptor activation pathway
G alpha (z) signalling events pathway
Phospholipase C-mediated cascade pathway
Transmembrane transport of small molecules pathway
GABA receptor activation pathway
G alpha (i) signalling events pathway
Signalling by NGF pathway
Signaling by PDGF pathway
Neuronal System pathway
DAG and IP3 signaling pathway
Signaling by Hedgehog pathway
NGF signalling via TRKA from the plasma membrane pathway
Opioid Signalling pathway
Calmodulin induced events pathway
Adenylate cyclase activating pathway pathway
Signal Transduction pathway
Transmission across Chemical Synapses pathway
Signaling by FGFR pathway
PLC beta mediated events pathway
G-protein mediated events pathway
Signaling by EGFR in Cancer pathway
PKA activation pathway
DAP12 interactions pathway
DAP12 signaling pathway
KEGG
GnRH signaling pathway pathway
Gap junction pathway
Purine metabolism pathway
Calcium signaling pathway pathway
Melanogenesis pathway
Vascular smooth muscle contraction pathway
Chemokine signaling pathway pathway
Progesterone-mediated oocyte maturation pathway
Dilated cardiomyopathy pathway
Oocyte meiosis pathway
Gastric acid secretion pathway
Pancreatic secretion pathway
Salivary secretion pathway
Bile secretion pathway
Calcium signaling pathway pathway
Melanogenesis pathway
Gap junction pathway
GnRH signaling pathway pathway
Purine metabolism pathway
Chemokine signaling pathway pathway
Vascular smooth muscle contraction pathway
Dilated cardiomyopathy pathway
Progesterone-mediated oocyte maturation pathway
Oocyte meiosis pathway
Gastric acid secretion pathway
Salivary secretion pathway
Bile secretion pathway
Pancreatic secretion pathway
INOH
GPCR Adenosine A2A receptor signaling pathway pathway
Purine nucleotides nucleosides metabolism pathway
GPCR signaling pathway
GPCR Adenosine A2A receptor signaling pathway pathway
GPCR signaling pathway
PID NCI
Regulation of nuclear beta catenin signaling and target gene transcription
Cross-References
SwissProt Q29450
TrEMBL
UniProt Splice Variant
Entrez Gene 281603
UniGene Bt.1165
RefSeq NM_174230 XM_005218439 XM_005218440 XM_005218441 XM_005218442 XM_005218443 XM_005218444
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL Z49806
GenPept CAA89894
RNA Seq Atlas 281603