Version 5.4
Bos taurus Gene: SMG5
Summary
InnateDB Gene IDBG-631625.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SMG5
Gene Name protein SMG5
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000009435
Encoded Proteins
IDBP-683186
protein SMG5
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000198952:
SMG5 is involved in nonsense-mediated mRNA decay (Ohnishi et al., 2003 [PubMed 14636577]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 3:14569447-14597121
Strand Forward strand
Band
Transcripts
ENSBTAT00000012415 ENSBTAP00000012415
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 8 interaction(s) predicted by orthology.
Predicted by orthology
Total 8 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0051721 protein phosphatase 2A binding
Biological Process
GO:0035303 regulation of dephosphorylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000198952
View Gene Order
ENSMUSG00000001415
View Gene Order
Pathway Predictions based on Human Orthology Data
NETPATH
REACTOME
REACT_75822
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_75886
Nonsense-Mediated Decay (NMD) pathway
REACT_71
Gene Expression pathway
REACT_198522
Nonsense-Mediated Decay (NMD) pathway
REACT_198528
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) pathway
REACT_233572
Gene Expression pathway
KEGG
hsa03015
mRNA surveillance pathway pathway
mmu03015
mRNA surveillance pathway pathway
INOH
PID NCI
hdac_classi_pathway
Signaling events mediated by HDAC Class I
telomerasepathway
Regulation of Telomerase
Cross-References
SwissProt
TrEMBL A4IFN9
UniProt Splice Variant
Entrez Gene 513598
UniGene Bt.61156
RefSeq NM_001083679
HUGO
OMIM
CCDS
HPRD
IMGT
EMBL BC134680 DAAA02007141
GenPept AAI34681
RNA Seq Atlas 513598

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca