InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: COX5A

Summary

InnateDB Gene

IDBG-631646.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

COX5A

Gene Name

Cytochrome c oxidase subunit 5A, mitochondrial

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000017267

Encoded Proteins

IDBP-683197

Cytochrome c oxidase subunit 5A, mitochondrial

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000178741:
Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer of proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit Va of the human mitochondrial respiratory chain enzyme. A pseudogene COX5AP1 has been found in chromosome 14q22. [provided by RefSeq, Jul 2008]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 21:34156312-34167331

Strand

Forward strand

Band

Transcripts

ENSBTAT00000022949

ENSBTAP00000022949

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004129	cytochrome-c oxidase activity
GO:0046872	metal ion binding

Biological Process

GO:1902600

hydrogen ion transmembrane transport

Cellular Component

GO:0005739	mitochondrion
GO:0005743	mitochondrial inner membrane
GO:0016020	membrane
GO:0045277	respiratory chain complex IV
GO:0070062	extracellular vesicular exosome