Bos taurus Gene: DMRT2
Summary
InnateDB Gene IDBG-631662.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DMRT2
Gene Name doublesex- and mab-3-related transcription factor 2
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000008062
Encoded Proteins
doublesex and mab-3 related transcription factor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000173253:
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila 'doublesex' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]
The protein encoded by this gene belongs to the DMRT gene family, sharing a DM DNA-binding domain with Drosophila \'doublesex\' (dsx) and C. elegans mab3, genes involved in sex determination in these organisms. Also, this gene is located in a region of the human genome (chromosome 9p24.3) associated with gonadal dysgenesis and XY sex reversal. Hence this gene is one of the candidates for sex-determining gene(s) on chr 9. [provided by RefSeq, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 8:43780986-43787918
Strand Reverse strand
Band
Transcripts
ENSBTAT00000010604 ENSBTAP00000010604
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 23 interaction(s) predicted by orthology.
Predicted by orthology
Total 23 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0042803 protein homodimerization activity
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0014807 regulation of somitogenesis
GO:0048706 embryonic skeletal system development
GO:2000287 positive regulation of myotome development
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
Cross-References
SwissProt
TrEMBL E1BC71
UniProt Splice Variant
Entrez Gene 514435
UniGene
RefSeq NM_001192373
HUGO HGNC:2935
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02022770
GenPept
RNA Seq Atlas 514435