Version 5.4
Bos taurus Gene: CMBL
Summary
InnateDB Gene IDBG-631739.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CMBL
Gene Name carboxymethylenebutenolidase homolog
Synonyms
Species Bos taurus
Ensembl Gene ENSBTAG00000010801
Encoded Proteins
IDBP-683291
carboxymethylenebutenolidase homolog (Pseudomonas)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000164237:
CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 20:63065548-63090743
Strand Forward strand
Band
Transcripts
ENSBTAT00000014308 ENSBTAP00000014308
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 11 interaction(s) predicted by orthology.
Predicted by orthology
Total 11 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0008152 metabolic process
Cellular Component
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Homo sapiens
Mus musculus
Gene ID
Gene Order
ENSG00000164237
View Gene Order
ENSMUSG00000022235
View Gene Order
Cross-References
SwissProt
TrEMBL F1N2I5
UniProt Splice Variant
Entrez Gene 516405
UniGene Bt.3203
RefSeq NM_001192983
HUGO HGNC:25090
OMIM
CCDS
HPRD
IMGT
EMBL DAAA02051220
GenPept
RNA Seq Atlas 516405

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca