InnateDB: Systems Biology of the Innate Immune Response

Bos taurus Gene: SNX3

Summary

InnateDB Gene

IDBG-631765.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SNX3

Gene Name

Sorting nexin-3

Synonyms

Species

Bos taurus

Ensembl Gene

ENSBTAG00000018801

Encoded Proteins

IDBP-683321

Sorting nexin-3

Protein Structure

Useful resources

Stemformatics EHFPI ImmGen

Entrez Gene

Summary

This gene does not have any Entrez summary - the following is the summary from its human ortholog ENSG00000112335:
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. [provided by RefSeq, Jul 2008]
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like most family members. This protein interacts with phosphatidylinositol-3-phosphate, and is involved in protein trafficking. A pseudogene of this gene is present on the sex chromosomes. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2014]

Gene Information

Type

Protein coding

Genomic Location

Chromosome 9:42370448-42417660

Strand

Forward strand

Band

Transcripts

ENSBTAT00000025026

ENSBTAP00000025026

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 39 interaction(s) predicted by orthology.

Predicted by orthology
Total	39 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0008289	lipid binding
GO:0019903	protein phosphatase binding
GO:0032266	phosphatidylinositol-3-phosphate binding
GO:0035091	phosphatidylinositol binding

Biological Process

GO:0006810	transport
GO:0006886	intracellular protein transport
GO:0015031	protein transport
GO:0032268	regulation of cellular protein metabolic process
GO:0033157	regulation of intracellular protein transport
GO:0033572	transferrin transport
GO:0042541	hemoglobin biosynthetic process

Cellular Component

GO:0005737	cytoplasm
GO:0005768	endosome
GO:0005769	early endosome
GO:0010008	endosome membrane
GO:0043231	intracellular membrane-bounded organelle
GO:0070062	extracellular vesicular exosome